NIBSC and the SoGAT advisory group are pleased to announce the 28th international workshop on standardisation.

The 2-day meeting will be hosted at the MHRA headquarters in Canary Wharf, London, UK and will cover topics including:

  • Challenges with detection due to genetic variability and different extraction efficiencies
  • The impact of changing methodologies on standardisation
  • Alternative approaches to understanding commutatbility
  • Point of impact testing – how can we standardise, and the role of SoGAT

This is a must attend event for anyone working in the infectious disease diagnostic setting, from laboratory scientists, assay manufacturers (not just qPCR assays but also point of impact tests, NGS and dPCR) Reference Laboratories, EQA providers, to those in a regulatory setting.

Benefits of attending

  • Networking with others working in the molecular diagnostics area
  • Opportunity to share your own experiences and exchange ideas with like-minded colleagues
  • Receive updates on current standardisation projects




  • Tweets will appear here soon


  • Registration

  • Morning session - SoGAT aims and Project overviews

    • Session 1 - Introductory session - Neil Almond, Chair - SoGAT

      • Review of SoGAT 2018 actions & Recap - Background to standardisation
  • Session 2 - Ask Experts - Chairs: Francois Xavier-Lery, WHO and Clare Morris, NIBSC

    • Update on all ongoing WHO diagnostic standardisation projects


    Session discussion

    • What infectious disease assays still require reference materials and what is the priority?
    • What are the challenges that lie ahead?
  • Lunch

    Buffet lunch provided

  • Afternoon session - Challenges for diagnostic assay standardisation - Part One

    • Session 3 - Commutability of reference materials - Chairs: Sheila Govind, NIBSC and Peter Vallone, NIST

      • dPCR for the Characterization of WHO International Standards: JCV and EBV - Megan Cleveland, NIST, USA
      • Alternative materials for HCV IS replacements - Jacqueline Fryer, NIBSC, UK
      • Viral fragmentation and extraction efficiency - Linda Cook, University of Washington, USA


      Session discussion

      • How can the SoGAT group work together to generate commutability data?
      • What data is needed; what data do laboratories already have?
  • Coffee

  • How efficient is your extraction method? - Overview and Chairs: Michael Chudy, PEI and Rob Anderson, NIBSC

    • Effect of 3 extraction platforms on NGS data - Simon Carne, PHE, UK
    • Impact of different extraction systems on HDV RNA quantitation - Harald H. Kessler, Medical University of Graz, Austria
    • Challenges of fungal extraction - Lewis White, Public Health Wales, UK


    Session discussion

    • Should we be running studies to compare extraction efficiency, does this data already exist?
  • End of day one

  • Morning session - Challenges for diagnostic assay standardisation - Part Two

    • Session 3 cont. Genetic Variability - Overview and Chairs: Jacqueline Fryer, NIBSC and Simon Carne, PHE

      • HPV variants and development of suitable reference materials - Dianna Wilkinson / Rob Anderson, NIBSC, UK
      • HIV - challenges of continual recombination - Indira Hewlett, FDA, USA
      • Development of diagnostic standards for molecular detection of respiratory viruses - Clare Morris, NIBSC, UK


      Session discussion

      • How are WHO panels currently used?
      • What do we need going forward?
  • Coffee

  • Session 4: dPCR and NGS in diagnostics - Chairs: Bert Niesters, QCMD and Neil Berry, NIBSC

    • dPCR vs qPCR - a statistical view point - Peter Vallone, NIST, USA
    • Guidelines for dPCR - Jim Huggett, LGC, UK
    • Quantification of hCMV by dPCR - Mojca Milavec, NIB, Slovenia
    • Quality assurance challenges of viral WGS assays for direct patient care - Tamyo Mbisa, PHE, UK


    Session discussion

    • How is dPCR being used in the diagnostic laboratory?
    • Does NGS have a routine clinical application and if so how is it used?
  • Lunch

    Buffet lunch provided

  • Afternoon session - Molecular point of care assays

    • Session 5: Standardising Point of Care testing - Chairs: Beatrice Vetter, FIND and Clare Morris, NIBSC

      • Validation of POC tests - Ute Stroher, WHO, Switzerland
      • Molecular POCT for respiratory viruses: the current landscape - Tristan Clark, University of Southampton, Faculty of Medicine, UK
      • Influenza / RSV POC - EQA data - Heinz Zeichhardt, INSTAND, Germany
  • Coffee

  • Manufacturers discussions

    • Point of impact testing - European perspective - Bert Niesters, QCMD


    Round table - Manufacturers discussion

    • How is LOD determined?
    • What reference materials are used for validation?
    • What does the ideal reference material need to look like?


    Session discussion

    • What additional validation do the end users need to carry out?
    • How are assays routinely monitored?
  • SoGAT 2019 - Summing up, actions going forward

  • Workshop close



MHRA Offices
1st Floor, 10 South Colonnade
Canary Wharf
E14 4PU

Tel: 020 3080 6000


From Canary Wharf DLR station, the site is best accessed via the southern exit onto South Colonnade.  The building is directly opposite to the right.

London Underground
Canary Wharf station has two entrances/exits - east and west - with accessible lifts located at both. The west exit is the most direct entrance/exit for us - follow signs for DLR and at the final set of escalators you should see Paperchase on your right.


The 10SC building does not offer parking however the Canary Wharf area has four underground public car parks offering 2,500 spaces.  Choose the best one for you here: https://canarywharf.com/getting-here/parking/


Ibis London Docklands Canary Wharf

1 Baffin Way, Off Preston Road, E14 9PE
Tel: +44 207 517 1100
Email: H2177@accor.com
Web: https://www.accorhotels.com/gb/hotel-2177-ibis-london-docklands-canary-wharf/index.shtml

Point A Hotel - Canary Wharf

1B Hertsmere Road West, London, E14 4AS
Tel: 020 7531 8100
Email: london.canarywharf@pointahotels.com
Web: https://www.pointahotels.com/our-hotels/canary-wharf/

Britannia International Hotel

Marsh Wall, London, E14 9SJ
Tel: +44 871 222 0042
Web: https://www.britanniahotels.com/hotels/the-international-hotel


In order to register for the event, please click the register button below. Please ensure you have all your details ready.

Upon completion an invoice is issued automatically via email to the booker. This includes a secure online credit card payment link and also details of how to make BACS payments etc.

* the non commercial rate is applicable for Charities / Third Sector / NHS / Government & Academic

Contact Us

MHRA have appointed Glasgows to organise the event and host the online registration process.

For more information about other MHRA events please visit the Conferences and Events page of the MHRA website: www.mhra.gov.uk.